CGM - Scientifique organisation

Department Gene Expression

Head of the department: Domenico LIBRI

  Last update: 09-Nov-2010

The Gene Expression Department is composed by 7 teams with scientific interests focused around the metabolism of RNA. RNA biogenesis and turn-over, as well as the multiple functions of RNA are studied in the Department. The team of  L. Kuras is interested in the mechanisms of transcription initiation and the role of co-activators. The Libri team studies the generation of the mRNP particle and the mechanisms of nuclear quality control.  Alternative splicing is the main subject of the Marie’s team, with a particular interest to the molecular mechanisms underlying some genetic diseases as Myotonic Dystrophy. The function of non-coding RNAs is the main subject of interest for the Bossi team. Both study the role of non-coding RNAs in gene expression regulation, respectively in the yeast and bacterial systems. F. Michel and colleagues work on the structure and function of autocatalytic RNAs. Finally, the Chavatte team is interested in the synthesis and regulation of selenoproteins in mammals.

The teams are classified following the surname of the team leaders. Please, click on the surname of a leader to go to the Web pages of his (her) team.