CGM - Scientifique organisation
Department Cellular and Integrative Biology
Head of the department: Annie SAINSARD-CHANET
Last update: 18-Sep-2009
The department is composed of five groups whose principal interests concern the biogenesis and functioning of large multi‑protein complexes (respiratory chains, photosynthetic complexes, mitochondrial translation machinery and mitochondrial import machinery). In parallel, detailed structure/function studies of some proteins are undertaken.
The groups use genetic, molecular biology, cell biology and biochemical approaches and work mainly with simple model systems (yeasts, filamentous fungi and purple bacteria). These models are used to study the role of mitochondria in different fundamental processes such as ageing and the control of longevity; they are also used to study the molecular basis of some human pathologies, such as mitochondrial diseases, atherosclerosis and cancer.
The teams are classified following the surname of the team leaders. Please, click on the surname of a leader to go to the Web pages of his (her) team.
| Responsable | Equipe |
| Chantal ASTIER | Biogenesis of bioenergetic complexes in the facultative photosynthetic proteobacterium, Rubrivivax gelatinosus |
| Nathalie BONNEFOY | Translation of mitochondrial RNA in the yeast S. pombe |
| Geneviève DUJARDIN | Biogenesis and function of mitochondrial respiratory complexes |
| Denis POMPON | Laboratory of membrane proteins engineering (LIPM) |
| Annie SAINSARD-CHANET | Senescence and mitochondria in Podospora anserina |
