CGM - Team attached to the Director
BIOINFOME: BioInformatics for Transcriptome & Proteome
Group leader: Hervé Delacroix
Last update: 28-Oct-2011
The lab
Hervé Delacroix, Professeur, Université Paris-Sud 11
Annie Glatigny, Ingénieur
Marie-Hélène Mucchielli-Giorgi, Maître de Conférences, UPMC
Our address
CNRS - Centre de Génétique Moléculaire
Avenue de la Terrasse - Bât. 24
91198 GIF-SUR-YVETTE Cedex
FRANCE
Phone : 33 (0)1 69 82 38 75
Research interest
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Selected publications
- Glatigny, A., Mathieu, L., Herbert, CJ., Dujardin, G., Meunier, B., Mucchielli-Giorgi, MH. (2011) An in silico approach combined with in vivo experiments enables the identification of a new protein whose overexpression can compensate for specific respiratory defects in Saccharomyces cerevisiae. BMC Syst Biol, 5 (1) 173.
- Nowak, J. K., Gromadka, R., Juszczuk, M., Jerka-Dziadosz, M., Maliszewska, K., Mucchielli, M. H., Gout, J. F., Arnaiz, O., Agier, N., Tang, T., Aggerbeck, L. P., Cohen, J., Delacroix, H., Sperling, L., Herbert, C. J., Zagulski, M., Betermier, M. (2011) A functional study of genes essential for autogamy and nuclear reorganization in Paramecium. Eukaryot Cell, 10 (3) 363-72.
- Bidard, F., Aït Benkhali, J., Coppin, E., Imbeaud, S., Grognet, P., Delacroix, H. and Debuchy, R. (2011) Genome-Wide Gene Expression Profiling of Fertilization Competent Mycelium in Opposite Mating Types in the Heterothallic Fungus Podospora anserina. PLoS ONE, 6 (6) e21476.
- Tyler, AI., Shearman, GC., Brooks, NJ., Delacroix, H., Law, RV., Templer, RH., Ces, O., Seddon, JM. (2011) Hydrostatic pressure effects on a hydrated lipid inverse micellar Fd3m cubic phase. Phys Chem Chem Phys, 13 (8) 3033-8.
- Bidard, F., Imbeaud, S., Reymond, N., Lespinet, O., Silar, P., Clave, C., Delacroix, H., Berteaux-Lecellier, V. and Debuchy, R. (2010) A general framework for optimization of probes for gene expression microarray and its application to the fungus Podospora anserina. BMC Res Notes, 3 (1) 171.
- Loe-Mie, Y., Lepagnol-Bestel, AM., Maussion, G., Doron-Faigenboim, A., Imbeaud, S., Delacroix, H., Aggerbeck, L., Pupko, T., Gorwood, P., Simonneau, M., Moalic, JM. (2010) SMARCA2 and other genome-wide supported schizophrenia-associated genes: regulation by REST/NRSF, network organization and primate-specific evolution. Hum Mol Genet, 19 (14) 2841-57.
- Maunoury, N., ..., Agier, N., Marisa, L., Vaubert, D., Delacroix, H., ... Aggerbeck, L., Kondorosi, E., Mergaert, P. (2010) Differentiation of symbiotic cells and endosymbionts in Medicago truncatula nodulation are coupled to two transcriptome-switches. PLoS One, 5 (3) e9519.
- Turpaev, K., Glatigny, A., Bignon, J., Delacroix, H. and Drapier, J.-C. (2010) Variation in gene expression profiles of human monocytic U937 cells exposed to various fluxes of nitric oxide. Free Radic Biol Med, 48 (2) 298-305.
- Bury-Moné, S., Nomane, Y., Reymond, N., Barbet, R., Jacquet, R., Imbeaud, S., Jacq, A. and Bouloc, P. (2009) Global analysis of extracytoplasmic stress signaling in Escherichia coli. PLoS Genetics, 5 (9) e1000651.
- Glatigny A., Delacroix H., Tang T., François N., Aggerbeck L., Mucchielli-Giorgi M-H. (2009) Characterisation and correction of signal fluctuations in successive acquisitions of microarray images. BMC Bioinformatics, 10 (1) 98.
- Bourens, M., Panozzo, C., Nowacka, A., Imbeaud, S., Mucchielli, M.-H. and Herbert, C.-J. (2009) Mutations in the Saccharomyces cerevisiae Kinase Cbk1p, Lead to a Fertility Defect That Can Be Suppressed by the Absence of Brr1p or Mpt5p (Puf5p), Proteins Involved in RNA Metabolism. Genetics, 183 (1) 161-73.
- Bourges, I., Mucchielli, M.-H., Herbert, C.-J., Guiard, B., Dujardin, G. and Meunier, B. (2009) Multiple Defects in the Respiratory Chain Lead to the Repression of Genes Encoding Components of the Respiratory Chain and TCA Cycle Enzymes. J Mol Biol, 23 (1) 23-42.
- Narjoz, C., Marisa, L., Imbeaud, S., Paris, A., Delacroix, H., Beaune, P., De Waziers, I. (2009) Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells. Chem Res Toxicol, 22 (5) 779-87.
- Lepagnol-Bestel, A., Zvara, A., Maussion, G., Quignon, F., Ngimbous, B., Ramoz, N., Imbeaud, S., Loe-Mie, Y., Benihoud, K., Agier, N., Salin, P., Cardona, A., Khung-Savatovsky, S., Kallunki, P., Delabar, J., Puskas, L., Delacroix, H., Aggerbeck, L., Delezoide, A., Delattre, O., Gorwood, P., Moalic, J. and Simonneau, M. (2009) DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome. Hum Mol Genet, 18 (8) 1405-14.
- Benoit, V., Mucchielli-Giorgi, M.-H., Dumont, B., Durosay, P., Reymond, N. and Delacroix, H. (2008) PPIDD: An extraction and visualisation method of biological protein-protein interfaces. Biochimie, 90 (4) 640-7.
- Marisa, L., Ichanté, J.-L., Reymond, N., Aggerbeck, L., Delacroix, H. and Mucchielli-Giorgi, M.-H. (2007) MAnGO: an interactive R-based tool for two-colour microarray analysis. Bioinformatics, 23 (17) 2339-41.
- Matsunaga, F., Glatigny, A., Mucchielli-Giorgi, M.-H., Agier, N., Delacroix, H., Marisa, L., Durosay, P., Ishino, Y., Aggerbeck, L. P. and Forterre, P. (2007) Genomewide and biochemical analyses of DNA-binding activity of Cdc6/Orc1 and Mcm proteins in Pyrococcus sp. Nucleic Acids Res, 35 (10) 3214-22.
- Tang, T., François, N., Glatigny, A., Agier, N., Mucchielli, M., Aggerbeck, L. and Delacroix, H. (2007) Expression ratio evaluation in two-colour microarray experimentsis significantly improved by correcting image mis-alignment. Bioinformatics, 23 (20) 2686-91.
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